Preparation lines for the pharmaceutical industry
The LIPROLINE preparation lines are intended for the manufacture of sterile liquids and include weighing of the components, mixing, sterile filtration, sterile storage and bottling. They are planned with the aid of 3D-CAD systems and take such features into account as an isolator for highly active substances or a control system which includes recipe management. Process-control systems permit recipe-based operation with automatic batch logging in accordance with CFR 21 Part 11. Further features such as explosion protection, powder input and handling or heating and cooling systems are available as options.
Cleaning systems for CIP / SIP
Three LIPROLINE concepts are available for CIP/SIP applications. Single-use CIP systems are suitable for the low-cost cleaning of small-volume systems with cleaning solutions which are used only once. They are also available in versions suitable for wall mounting. Fully automatic CIP systems are used for medium to large process plants. Their design ensures easy handling and can be extended with options such as heat exchangers, data logging, conductivity measurement or a connection for ultrapure steam. The CIP recirculation systems are suitable for the cleaning of large-volume systems, since the cleaning solution is recirculated. Their bus interface permits connection to a higher-level control system. The careful microbiological cleaning prevents cross-contamination to and from other production plants.
Decontamination of pharmaceutical wastewater
Pharmaceutical and biotechnological wastewater can be treated with the LIPROLINE decontamination systems. These treat the wastewater generated by research laboratories or production plants and are available in versions designed for fully automatic batch or continuous operation. The inactivated wastewater can then be discharged into the normal wastewater network of the factory. An exhaust-air deodorisation unit is available as an option in order to prevent unpleasant smells. The LIPROLINE systems for the treatment of pharmaceutical wastewater remove the water from the solutions to be treated and thus greatly reduce the amount of materials which has to be disposed of. In addition, the special evaporator technology inactivates certain active substances. Depending on the application, this can also be achieved by low-cost UV oxidisation of the substances with the aid of the UV units of the LIPROLINE range.
All LIPROLINE systems are compactly mounted on a frame, are fully self-draining, are pre-qualified and can be sterilised with steam at temperatures of up to 135 °C.
LIPROLINE - good solutions depend on intelligent concepts